Dr. Ambalika Tanak
1.Multiplexed cytokine detection using electrochemical point-of-care sensing device towards rapid sepsis endotyping
Biosensors and Bioelectronics https://doi.org/10.1016/j.bios.2020.112726
Direct Electrochemical Technique Targeting Sepsis (DETecT Sepsis) device platform provides the first proof of concept for rapid diagnostic screening of sepsis leveraging a host immune response biomarker panel. The results of this research demonstrate a robust, sensitive, specific, and stable which is highly expected from a point-of-care device helpful towards disease endotypying for effective clinical management of sepsis at the patient bedside.
2. Establish pre-clinical diagnostic efficacy for parathyroid hormone as a point-of-surgery-testing-device (POST)
Scientific Reports (in-print)
This work focuses on clinically validating the developed sensor with 40 patient samples who have undergone parathyroidectomy for its use as a clinical utility as a guide to surgeons. The results obtained from READ platform during clinical validation correlated well (r=0.99) with commercially available clinical laboratory method (Cobas, Roche Diagnostics, IA) to measure PTH levels with a turn-around time of less than 15 min.
3. CLIP: Carbon Dioxide testing suitable for Low power microelectronics and IOT interfaces using Room temperature Ionic Liquid Platform
Scientific Reports https://doi.org/10.1038/s41598-020-59525-y
We have described the functionality and utility of a developed low-power microelectronic research prototype integrated with an RTIL-based electrochemical sensing platform for the detection of CO2 in exhaled breath.