Dr. Badrinath Jagannath
A Sweat-based Wearable Enabling Technology for Real-time Monitoring of IL-1β and CRP as Potential Markers for Inflammatory Bowel Disease
Journal: Inflammatory Bowel Diseases, https://doi.org/10.1093/ibd/izaa191
This work demonstrates a wearable sweat sensor for real-time tracking of inflammatory markers in passively expressed eccrine sweat toward better management of inflammatory bowel disease. Furthermore, this is the first study to report and quantify the presence of CRP in human eccrine sweat.
CLIP: Carbon Dioxide testing suitable for Low power microelectronics and IOT interfaces using Room temperature Ionic Liquid Platform
In this work, a portable, hand-held electrochemical CO2 monitor was developed with room temperature ionic liquid as the sensing element. The device was tested to measure breath CO2 in 6 subjects and reported a linearity (R2>0.9) over a wide dynamic range of 400- 12000 ppm.
Non-faradaic electrochemical impedimetric profiling of procalcitonin and C-reactive protein as a dual marker biosensor for early sepsis detection
Journal: Analytica Chimica Acta: X, https://doi.org/10.1016/j.acax.2019.100029
A multiplexed electrochemical biosensor for detection of sepsis biomarkers was developed. The sensing platform demonstrated high sensitivity with a limit of detection of 0.1 ng mL-1 for the biomarkers in serum and whole blood using electrochemical impedance spectroscopy. Such a sensing platform can be useful for rapid screening of sepsis.